Impact of pH modifiers and drug exposure on the solubility of pharmaceutical products commonly administered through water delivery systems
نویسندگان
چکیده
Large contemporary swine-production systems routinely turn to water delivery systems as a method for administering approved therapeutic agents when circumstances call for mass treatment of entire pig populations. Water medications are used for reasons ranging from the relative ease of the method compared to injectables, to the decreased likelihood of needle-stick injuries and broken needles found in pigs at slaughter, to a desire for a rapid response to therapy. Underlying all decisions to use waterlines for delivering antimicrobials, vaccines, aspirin, vitamins, and electrolytes are assumptions that the medications reach all pigs; that all pigs, including sick pigs, consume the medications; that medications are absorbed; that water delivery systems are functional; and that medicators deliver the desired concentration of medication.
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